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Oligopeptide-51 and -55 : anti-hyperpigmentation peptides, studied for solar spots and senile lentigines Nonapeptide-1 : -MSH antagonist, melanogenesis inhibitor in cosmetic research Agouti signaling protein (ASIP) : physiological MC1R antagonist, oriented toward pheomelanin rather than eumelanin Experimental pigmentation models Studies classically use: murine B16 melanocytes (F10 line, F1 line for differentiation), primary human melanocytes (NHEM), melanocyte-keratinocyte co-cultures , pigmented skin equivalents (MelanoDerm, Phenion FT)

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Bigfoot Biomedical

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Sommer, T

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A new study presented at the 2025 Annual Meeting of the American Academy of Orthopaedic Surgeons examined how the timing of a patients last dose of a GLP-1 agonists prior to total knee arthroplasty (TKA) or total hip arthroplasty (THA) influences anesthesia-related complications such as delayed emergence, aspiration, aspiration pneumonitis, and conversion to intubation

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Furthermore, studies in human atrial- and ventricular-programmed induced pluripotent stem cells or engineered heart tissues will allow for more long-term studies and higher throughput in elucidating LCAC pathophysiology and potential targeting strategies

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